Arginine Plus™ by Metagenics – Cardiovascular Nutrition Support
Arginine Plus by Metagenics combines L-arginine with an active form of folate in a focused tablet formula for cardiovascular health support. Rather than supplying a broad multivitamin blend, it brings together two nutrients involved in complementary aspects of vascular nutrition: an amino acid used in nitric oxide production and folate involved in homocysteine metabolism. Each two-tablet serving provides 1.5 g of L-arginine and 665 mcg DFE of folate, along with 10 mg of glycine. The bottle contains 120 tablets.*
Key Arginine Plus Benefits
- Provides nutritional support for healthy blood flow through L-arginine, a precursor the body uses to make nitric oxide.*
- Supplies active folate support with calcium L-5-methyltetrahydrofolate, rather than folic acid, for people discussing folate-form preferences with their practitioner.*
- Supports healthy homocysteine metabolism as part of a balanced approach to cardiovascular nutrition.*
How Arginine Plus Works
The body uses L-arginine as a starting material for nitric oxide. This signaling molecule participates in normal blood vessel relaxation, helping explain arginine's role in nitric oxide support. Providing a precursor is not the same as guaranteeing an immediate increase in nitric oxide or a noticeable exercise effect; the body's response depends on its existing nutritional and physiological needs.*
Key Functional Ingredients Include:
- L-Arginine: This amino acid provides the central component of the formula's vascular function support. Its nutritional role is distinct from a stimulant or a short-term workout booster.*
- L-5-methyltetrahydrofolate: An active folate form involved in the normal processing of homocysteine. It complements arginine by addressing a different nutritional pathway rather than duplicating the amino acid's role.*
- Glycine: A second amino acid included at 10 mg per serving. Its presence does not make this formula a protein replacement or justify comparing it with high-dose glycine products.
A targeted amino acid supplement is best considered alongside your diet and existing supplements. Review overlapping folate and arginine sources with your practitioner rather than automatically combining several cardiovascular formulas.
Arginine Plus Is Formulated For
- Adults seeking practitioner-guided nutritional support for normal blood vessel function.*
- People who prefer a tablet combining L-arginine and active folate rather than purchasing those nutrients separately.
- Adults building a cardiovascular wellness routine around balanced meals, appropriate activity, and individualized healthcare guidance.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner before starting a new supplement. Ready to find the right fit? Access Now to schedule a consultation with our licensed wellness professionals at Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Amino Acid and Cardiovascular Supplements collections.
Recommendation: Take two tablets two times daily or as directed by your healthcare practitioner.
Serving Size: 2 Tablets
Servings Per Container: 60
Total Carbohydrate ... <1 g
Dietary Fiber ... <1 g
Folate (as calcium L-5-methyltetrahydrofolate) ... 665 mcg DFE
L-Arginine ... 1.5 g***
Glycine ... 10 mg***
**Percent Daily Values are based on a 2,000 calorie diet.
***Daily Value not established.
Other Ingredients: Microcrystalline cellulose, cellulose, stearic acid (vegetable), silica, calcium silicate, croscarmellose sodium, and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).
Storage: Keep tightly closed in a cool, dry place. Do not refrigerate.
Frequently Asked Questions About Arginine Plus
What are the main benefits of Arginine Plus?
Arginine Plus supports cardiovascular nutrition by combining an amino acid used in nitric oxide production with active folate involved in homocysteine metabolism. These are complementary roles: arginine supplies a precursor for normal vascular signaling, while folate supports a separate nutrient-processing pathway. The formula is intended for ongoing nutritional support, not an immediate energy boost or a promise of improved athletic performance. Discuss your goals and existing supplements with your healthcare practitioner.*
Who should consider Arginine Plus?
Adults interested in a focused L-arginine and active folate formula may wish to discuss Arginine Plus with their healthcare practitioner. The two-tablet serving and 120-tablet bottle make it important to distinguish serving size from daily directions: the manufacturer recommends two tablets two times daily unless your practitioner directs otherwise. It is not a substitute for a complete diet or individualized care. Pregnancy, nursing, medications, and relevant medical history require a suitability review before use.
Are there side effects or precautions with Arginine Plus?
L-arginine supplements can cause digestive discomfort, including nausea or diarrhea, in some people; individual tolerance varies. Do not exceed your practitioner’s directions, and stop use and seek advice if you develop unwanted symptoms. The manufacturer specifically advises consultation before use during pregnancy or nursing, when taking medications, or with a history of heart attack or kidney impairment. Keep this product away from children, and have your practitioner review your complete medication and supplement list.
How does Arginine Plus fit into an overall wellness routine?
Think of Arginine Plus as targeted cardiovascular nutrition rather than an all-purpose wellness supplement. Its L-arginine and active folate can complement balanced meals, appropriate physical activity, and regular practitioner follow-up. It does not replace dietary protein, a varied intake of essential nutrients, or prescribed care. Review other products you use for overlapping arginine or folate, and let your healthcare practitioner determine whether this combination fits your needs and how long to use it.*
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.