Circadian PM™ by Researched Nutritionals – Nighttime Relaxation and Sleep Support Capsules
Circadian PM™ sleep support capsules by Researched Nutritionals combine amino acids and botanical extracts in a vegetarian capsule formula for evening use. This 90-capsule product brings together CalmNight™ Blend and HistaCalm™, rather than relying on a single ingredient or added melatonin.
For adults considering melatonin-free sleep support, the distinction matters: this formula includes glycine, L-theanine, lemon balm, valerian and 5 HTP, alongside other plant extracts. Its two blends disclose their combined weights, not individual ingredient doses. That makes it a different choice from a standalone amino acid with a separately listed amount.
Key Circadian PM™ Benefits
- Supports nighttime relaxation with a combination of amino acids and botanical extracts chosen for an evening wind-down routine, rather than daytime stimulation.
- Provides L-theanine and lemon balm to support a calm response to everyday stress as you transition from daytime activity toward rest.
- Includes nutrients involved in normal nervous-system signaling, complementing consistent bedtimes and a restful evening environment.
How Circadian PM™ Works
Settling down involves both the signals exchanged between nerve cells and the habits that tell your body the day is ending. Circadian PM™ combines ingredients with different roles in that process. Glycine participates in nerve communication, while 5 HTP supplies a building block used to make serotonin. L-theanine and lemon balm fit the formula's relaxation focus.
These are distinct functions, not interchangeable versions of melatonin. A blend containing several ingredients also deserves a full medication review: adding more calming or serotonin-related products is not automatically a better approach.
Key Functional Ingredients Include:
- Glycine: Participates in both excitatory and inhibitory nerve signaling. Inhibitory signals help regulate nerve-cell activity, while excitatory signals carry other essential messages. This normal communication role explains why glycine belongs in a nervous-system-focused formula.
- Valerian Extract: Supplies compounds from Valeriana officinalis root, a botanical traditionally used in bedtime preparations. It contributes the root-extract component of this nighttime combination; it is not melatonin and should not be combined with alcohol or sedatives.
- Lemon Balm Extract: Provides Melissa officinalis leaf constituents associated with calmness. Supporting a calmer response to everyday demands can help make the transition to a quieter evening feel more manageable, without making this botanical a replacement for healthy sleep habits.
- L-theanine: Is an amino acid associated with relaxed mental activity and the response to everyday stress. Its role here is to support winding down, not to supply a sleep hormone or act as a daytime stimulant.
- 5 HTP (5-hydroxytryptophan): Is converted by the body into serotonin, a messenger involved in normal sleep-wake regulation. Because it affects this pathway, medication compatibility is particularly important; do not combine it with serotonin-affecting medicines without physician supervision.
Circadian PM™ Is Formulated For
- Adults seeking a multi-ingredient evening formula without added melatonin.
- People who prefer vegetarian capsules and want to review a combined botanical and amino-acid approach with their healthcare professional.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner before starting a new supplement. Ready to find the right fit? Access Now to schedule a consultation with our licensed wellness professionals at Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Researched Nutritionals collection.
Recommendation: As a dietary supplement, take 3 capsules once daily before bed, or as directed by your healthcare professional.
Serving Size: 3 Capsules
Servings Per Container: 30
CalmNight™ Blend ... 2148 mg †
Glycine, Valerian Extract (Valeriana officinalis) (root), CurcuWIN™ Turmeric Extract, Lemon Balm Extract (Melissa officinalis) (leaf), Magnolia Extract (Magnolia officinalis) (bark), 5 HTP (5-hydroxytryptophan), L-theanine, PharmaGABA® (Gamma-aminobutyric acid)
HistaCalm™ ... 126 mg †
Black Cumin Extract (Nigella sativa) (seed), Stinging Nettle Extract (leaf)
** Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
Other Ingredients: Vegetarian cellulose (capsule shell)
Does Not Contain: Manufactured without milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, corn and gluten. Produced in a facility that may process other ingredients containing these allergens.
Additional precautions: Valerian can cause headache, stomach upset, mental dullness, excitability, uneasiness or vivid dreams. Avoid alcohol and sedatives, and do not drive if drowsy. Long-term valerian safety is unknown; withdrawal symptoms can follow abrupt discontinuation after chronic use. Rare liver injury has been reported, often with other herbs. Discuss ongoing use and any medications with your healthcare professional. 5 HTP can cause nausea, vomiting, diarrhea, headache, difficulty sleeping or palpitations. Do not combine with antidepressants, anti-anxiety medicines or other serotonin-affecting drugs without physician supervision because of the risk of serotonin syndrome. Avoid combining with St. John’s wort or SAM-e. Linezolid and carbidopa require specific medication review. Tell your clinician before a 5-HIAA urine test because 5 HTP can affect the result. Seek urgent medical care for agitation, fever, confusion or rapid heartbeat after a potentially interacting combination.
Additional precautions: Manufacturer California notice: This product contains herbs and / or minerals which come from the soil. As such, it may contain small amounts of naturally occurring chemicals. CA WARNING: Can expose you to lead, a reproductive toxicant. See www.P65Warnings.ca.gov/food
Frequently Asked Questions About Circadian PM™
What are the benefits of Circadian PM™?
Circadian PM™ is designed for nighttime relaxation and sleep support without added melatonin. Its CalmNight™ Blend combines glycine, valerian, turmeric, lemon balm, magnolia, 5 HTP, L-theanine and PharmaGABA®, while HistaCalm™ contains black cumin and stinging nettle. L-theanine and lemon balm support the relaxation focus; glycine and 5 HTP have roles in normal nerve signaling. Individual ingredient amounts are not disclosed, so this combination should not be treated as equivalent to a separately dosed single-ingredient supplement.
Who should take Circadian PM™?
Circadian PM™ is an option for adults considering a vegetarian, multi-ingredient supplement for their evening routine. The recommended serving is 3 capsules before bed, and the 90-capsule bottle lists 30 servings. It is not appropriate during pregnancy or nursing. People taking antidepressants, anti-anxiety medicines, sedatives or other regular medications need a clinician's review before use because this formula combines serotonin-related 5 HTP with calming botanicals. A melatonin-free formula still requires an individualized safety assessment.
Are there any side effects of taking Circadian PM™?
The manufacturer's warning is: Do not use while pregnant or nursing. Valerian can cause drowsiness, headache, stomach upset or vivid dreams; avoid alcohol and sedatives. 5 HTP can cause nausea, vomiting, diarrhea or palpitations. Do not combine it with serotonin-affecting medicines without physician supervision, or with St. John’s wort or SAM-e. Ask specifically about linezolid, carbidopa and 5-HIAA testing. Long-term valerian use needs review because abrupt discontinuation can cause withdrawal symptoms; rare liver injury has been reported. The manufacturer also provides a California warning about lead exposure. Review the additional precautions above before use.
How does Circadian PM™ support overall health?
Circadian PM™ focuses on the relaxation side of a consistent nighttime routine rather than providing broad vitamin or mineral nutrition. Glycine participates in normal nerve communication, 5 HTP is a serotonin precursor, and L-theanine and lemon balm complement the evening calming focus. These roles fit alongside regular bedtimes, reduced late-evening stimulation and an appropriate sleep environment. The formula does not contain added melatonin, and its proprietary blends do not disclose individual ingredient amounts. It should complement healthy habits, not replace assessment of persistent sleep difficulties.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.