Hypo-Gest by Priority One – Digestive Enzyme Support for Meal Breakdown
Hypo-Gest tablets by Priority One combine digestive enzymes, betaine hydrochloride and ox bile for support with the breakdown of food. Unlike an enzyme-only formula, this supplement brings together acid support, protein-digesting enzymes and bile components involved in handling dietary fat.
The formula spans stomach and intestinal digestive functions rather than focusing on just one food component. Bottle versions differ: the current 120-tablet manufacturer label and the archived 250-tablet label below have different serving sizes and enzyme amounts. Match the facts and directions to your bottle; do not transfer a serving instruction from one size to the other.
Key Hypo-Gest Benefits
- Supports protein digestion through pepsin and other enzymes that help break large dietary proteins into smaller pieces.
- Provides gastric acid support with betaine hydrochloride, complementing the acidic environment in which stomach enzymes normally work.
- Supports fat digestion through bile components and lipase activity, alongside amylase activity that helps break down starch from meals.
How Hypo-Gest Works
Digestion uses different tools at different stages. Stomach acid helps unfold proteins, making them accessible to enzymes such as pepsin. Farther along, pancreatic enzymes help split proteins, fats and starches. Bile components help fats disperse so enzymes can reach them. Hypo-Gest combines these distinct functions; adding acid is not the same as adding an enzyme, and bile itself is not an enzyme.
Key Functional Ingredients Include:
- Betaine HCL: Supplies hydrochloride as an acid source. An acidic stomach environment supports the action of pepsin and helps prepare dietary protein for digestion. Acid-containing supplements are not appropriate for every digestive concern; review the cautions before use.
- Pepsin: Breaks bonds within proteins, producing smaller protein fragments. It works in an acidic environment, which explains why this stomach enzyme appears alongside betaine hydrochloride rather than serving the same role as it.
- Pancreatin: Supplies several digestive enzyme activities rather than a single enzyme. Its amylase acts on starch, lipase acts on fats and protease acts on proteins. These complementary activities address different components of a mixed meal.
- Ox Bile Extract: Supplies bile components involved in dispersing dietary fats. This helps make fats accessible to digestive enzymes and supports their normal processing in the intestine. Its animal origin also makes Hypo-Gest unsuitable for vegetarian or vegan diets.
- Bromelain: Provides protein-breaking enzymes from pineapple. Its role is to split protein bonds, complementing the formula's other proteases without replacing the separate functions of starch-digesting amylase or fat-digesting lipase.
Hypo-Gest Is Formulated For
- People whose healthcare practitioner recommends a combination of digestive enzymes, acid support and bile components with meals.
- Those able to use animal-derived ingredients and follow the directions for their specific Hypo-Gest bottle version.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner before starting a new supplement. Ready to find the right fit? Access Now to schedule a consultation with our licensed wellness professionals at Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Digestion, GI Health Supplements, and Priority One collections.
120-Tablet Bottle — Current Manufacturer Label
Recommendation: Take four (4) tablets before meals or as directed by your physician.
Serving Size: Four (4) Tablets
Servings Per Container: 30
Stomach Ingredients:
Betaine HCL 98% ... 660mg **
L-Glutamic Acid ... 660mg **
Pepsin (1:3,000) ... 600mg **
Papain (2,850USP/mg) ... 316mg **
Intestine Ingredients:
Pancreatin (10x) ... 950mg **
Amylase ... 237,500USP **
Lipase ... 19,000USP **
Protease ... 237,500USP **
Bromelain (3,600MCU/g) ... 200mg **
Protease (Aspergillus spp.) (2,000SAP/g 200LAP/g) ... 300mg **
Perilla (leaf) (Perilla frutescens) Extract 8:1 ... 300mg **
Ox Bile Extract (45% cholic acid) ... 240mg **
**Daily Value not established.
Other Ingredients: Di-calcium phosphate, silicon dioxide, stearic acid (vegetable), microcrystalline cellulose, magnesium stearate (vegetable), croscarmellose sodium, methyl cellulose.
Does Not Contain: Contains no preservatives.
Storage: Keep container tightly closed, store in a cool, dry place.
250-Tablet Bottle — Archived Manufacturer Label
This manufacturer's label is archived by the NIH Dietary Supplement Label Database. It differs from the current 120-tablet formula. Confirm that your bottle matches this label before following these directions.
Recommendation: Take three (3) tablets before meals or as directed by your physician.
Serving Size: Three (3) Tablets
Servings Per Container: 83
Stomach Ingredients:
Betaine HCL ... 660mg **
L-Glutamic Acid ... 660mg **
Pepsin (1:3,000) ... 600mg **
Papain (3,000USP/mg) ... 300mg **
Intestine Ingredients:
Pancreatin (8x) ... 399mg **
Amylase ... 79,800USP **
Lipase ... 13,167USP **
Protease ... 79,800USP **
Pancreolipase ... 201mg **
Amylase (25,000SKB/g) ... 120mg **
Bromelain (3,600MCU/g) ... 200mg **
Protease (Aspergillus spp.) (2,000SAP/g) ... 300mg **
Perilla (leaf) (Perilla frutescens) 8:1 ... 300mg **
Ox Bile Extract ... 240mg **
**Daily Value not established.
Other Ingredients: Di-calcium phosphate, silicon dioxide, dextrin, calcium lactase, stearic acid (vegetable), saccharose, microcrystalline cellulose, magnesium stearate (vegetable), croscarmellose sodium, methyl cellulose.
Contains: Contains milk (starting material for pepsin)
Does Not Contain: Contains no preservatives.
Storage: Keep container tightly closed, store in a cool, dry place.
The current bottle's stronger pregnancy and breastfeeding restriction takes precedence: do not use during pregnancy or breastfeeding. Discuss medicines and ingredient allergies with your healthcare practitioner before using Hypo-Gest.
Frequently Asked Questions About Hypo-Gest
What are the benefits of Hypo-Gest?
Hypo-Gest supports the digestive breakdown of proteins, fats and starches by combining enzymes with betaine hydrochloride and ox bile. Pepsin and other proteases split proteins into smaller pieces, while pancreatin supplies activities for several meal components. Ox bile contributes to fat handling rather than functioning as an enzyme itself. This combination distinguishes Hypo-Gest from an enzyme-only supplement, but its acid-containing formula requires careful attention to the cautions and your practitioner's advice.
Who should take Hypo-Gest?
Hypo-Gest is intended for people whose practitioner recommends digestive enzymes together with acid and bile support. It is not suitable for vegetarians or vegans because it contains ox bile. The 120-tablet and archived 250-tablet labels differ, so check your bottle's formula and directions rather than assuming the sizes are interchangeable. The archived 250-tablet label also declares milk. People with relevant ingredient allergies need individual guidance, and the current label says not to use during pregnancy or breastfeeding.
Are there any side effects of taking Hypo-Gest?
Bromelain can cause stomach upset or diarrhea. Do not use Hypo-Gest during pregnancy or breastfeeding. The label says to stop taking Papain at least two weeks before surgery and use caution with low blood sugar. Consult your healthcare provider before use with active peptic ulcers, gastritis, acid reflux, a liver condition or a history of gallbladder removal. Review medicines and allergies, including the archived 250-tablet label's milk declaration, with your practitioner. Keep out of reach of children. The full manufacturer cautions above apply; Hypo-Gest is not suitable for vegetarian or vegan diets.
How does Hypo-Gest support overall health?
Hypo-Gest focuses on a foundational digestive task: breaking food into smaller components that the body can process. Its enzymes address protein, starch and fat, while betaine hydrochloride supplies acid and ox bile contributes bile components. These are complementary roles, not a substitute for eating a balanced diet. The formula does not supply the nutrients of a meal or replace prescribed digestive care. Choosing the correct bottle directions and reviewing acid-related cautions are important parts of using this supplement appropriately.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.