MitoSpark™ by NuMedica – Advanced Cellular Energy and Healthy Aging Support
MitoSpark is a premium cellular energy support formula from NuMedica designed to promote healthy aging at the mitochondrial level. Featuring nine clinically relevant botanicals and compounds — including Urolithin A, Spermidine Trihydrochloride, and Resveratrol — MitoSpark targets the foundational cellular processes of autophagy and mitophagy that decline with age, helping the body clear damaged cells and dysfunctional mitochondria to support lasting metabolic vitality.
Key MitoSpark Benefits
- Supports autophagy and mitophagy — the body's natural cellular housekeeping processes
- Promotes mitochondrial health and cellular energy production
- Provides broad-spectrum antioxidant support from polyphenol-rich botanicals
- Supports brain health, cardiovascular function, and immune resilience
- Formulated for anti-aging support and healthy longevity
How MitoSpark Works
As the body ages, its ability to carry out autophagy — the natural process that removes damaged proteins and worn-out cell parts — gradually declines. Mitophagy, a specialized form of autophagy that clears away unhealthy mitochondria, is especially important because mitochondria help produce energy for the body. When mitophagy becomes less efficient, it may contribute to lower energy levels, faster cellular aging, and increased oxidative stress. MitoSpark contains a concentrated blend of ingredients that have been studied for their ability to support these important cellular processes. Urolithin A, a compound derived from pomegranate nutrients, has been shown to help activate mitophagy in human muscle tissue. Spermidine, a naturally occurring compound, is widely researched for supporting autophagy, healthy brain function, cardiovascular health, and healthy aging.
Key Functional Ingredients Include:
- Gynostemma (Actiponin®†): Adaptogenic herb standardized for gypenosides; supports AMPK activation, energy metabolism, and general cellular health
- Pomegranate Hull Extract: Primary precursor to Urolithin A; supports mitophagy activation and antioxidant defense
- Gotu Kola: Traditionally used for cognitive and vascular support; promotes healthy circulation and brain-protective compounds
- Grape Seed Extract: Potent oligomeric proanthocyanidins (OPCs) supporting cardiovascular health and oxidative stress reduction
- Urolithin A: Bioactive postbiotic directly shown to activate mitophagy and support muscle cellular health in clinical studies
- Green Tea Extract: Rich in EGCG; supports metabolic health, antioxidant activity, and cellular signaling
- Resveratrol: Polyphenol from Polygonum cuspidatum; activates SIRT1 longevity pathways and supports mitochondrial function
- Maritime Pine Bark Extract: Supports vascular integrity, endothelial function, and systemic antioxidant capacity
- Spermidine Trihydrochloride: Naturally occurring polyamine; one of the most potent known inducers of general autophagy with neuroprotective and cardiovascular benefits
MitoSpark is free from milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, and soy, and is encapsulated in vegetable capsules — making it appropriate for vegetarians and those with common food sensitivities.
MitoSpark Is Formulated For
- Adults focused on healthy aging and longevity support
- Individuals seeking to support mitochondrial health and sustainable cellular energy
- Those interested in evidence-informed anti-aging supplements featuring autophagy-supporting compounds
- Adults supporting brain health, immune function, and cardiovascular resilience with polyphenol-rich formulas
- Practitioners looking for a comprehensive mitophagy support formula for active aging patients
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also want to explore our Anti-Oxidants Supplements collection.
Recommendation: Take three capsules once per day or as directed by your healthcare practitioner.
Serving Size: 3 Capsules
Servings Per Container: 30
Gynostemma (as Gynostemma pentaphyllum (leaf) extract† [Actiponin®], Gynostemma pentaphyllum (leaf) extract) ... 450 mg
Pomegranate (Punica granatum) (hull) extract (40% ellagic acid) ... 350 mg
Gotu Kola (Centella asiatica) (leaf) ... 250 mg
Grape (Vitis vinifera) (seed) extract (95% proanthocyanidins) ... 250 mg
Urolithin A ... 215 mg
Green Tea (Camellia sinensis) (leaf) extract (50% polyphenols) ... 200 mg
Resveratrol (from Polygonum cuspidatum (root) extract) ... 200 mg
Maritime Pine (Pinus pinaster) (bark) extract (95% proanthocyanidins) ... 100 mg
Spermidine Trihydrochloride ... 10 mg
Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), magnesium stearate, silicon dioxide.
Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
Warnings/Cautions: Keep out of reach of children. Keep tightly closed in a cool, dry place.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
†Actiponin® is a registered trademark of TG Biotech Co., Ltd.