MitoSpark™ 90 ct by NuMedica

MitoSpark™ by NuMedica – Advanced Cellular Energy and Healthy Aging Support

MitoSpark™ is a premium cellular energy support formula from NuMedica designed to promote healthy aging at the mitochondrial level. Featuring nine clinically relevant botanicals and compounds — including Urolithin A, Spermidine Trihydrochloride, and Resveratrol — MitoSpark™ targets the foundational cellular processes of autophagy and mitophagy that decline with age, helping the body clear damaged cells and dysfunctional mitochondria to support lasting metabolic vitality.

Key MitoSpark™ Benefits

• Supports autophagy and mitophagy — the body's natural cellular housekeeping processes
• Promotes mitochondrial health and cellular energy production
• Provides broad-spectrum antioxidant support from polyphenol-rich botanicals
• Supports brain health, cardiovascular function, and immune resilience
• Formulated for anti-aging support and healthy longevity

How MitoSpark™ Works

As the body ages, the efficiency of autophagy — the cellular process responsible for clearing damaged proteins and organelles — naturally declines. Mitophagy, a selective form of autophagy that targets dysfunctional mitochondria, is particularly critical: impaired mitophagy is associated with reduced energy output, accelerated cellular aging, and increased oxidative burden. MitoSpark™ delivers a concentrated blend of compounds with complementary mechanisms shown in preclinical and clinical research to support these pathways. Urolithin A, a postbiotic metabolite produced from pomegranate ellagitannins, has demonstrated direct mitophagy-activating effects in human skeletal muscle. Spermidine, a naturally occurring polyamine, is one of the most studied autophagy inducers known, with evidence linking it to neuroprotection, cardiovascular health, and longevity-related gene expression.

Key Functional Ingredients Include:

• Gynostemma (Actiponin®, 450 mg): Adaptogenic herb standardized for gypenosides; supports AMPK activation, energy metabolism, and mitochondrial biogenesis
• Pomegranate Hull Extract — 40% Ellagic Acid (350 mg): Primary precursor to Urolithin A; supports mitophagy activation and antioxidant defense
• Gotu Kola — Centella asiatica (250 mg): Traditionally used for cognitive and vascular support; promotes healthy circulation and brain-protective compounds
• Grape Seed Extract — 95% Proanthocyanidins (250 mg): Potent oligomeric proanthocyanidins (OPCs) supporting cardiovascular health and oxidative stress reduction
• Urolithin A (215 mg): Bioactive postbiotic directly shown to activate mitophagy and support muscle cellular health in clinical studies
• Green Tea Extract — 50% Polyphenols (200 mg): Rich in EGCG; supports metabolic health, antioxidant activity, and cellular signaling
• Resveratrol (200 mg): Polyphenol from Polygonum cuspidatum; activates SIRT1 longevity pathways and supports mitochondrial function
• Maritime Pine Bark Extract — 95% Proanthocyanidins (100 mg): Supports vascular integrity, endothelial function, and systemic antioxidant capacity
• Spermidine Trihydrochloride (10 mg): Naturally occurring polyamine; one of the most potent known inducers of general autophagy with neuroprotective and cardiovascular benefits

MitoSpark™ is free from milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, and soy, and is encapsulated in vegetable capsules — making it appropriate for vegetarians and those with common food sensitivities.

MitoSpark™ Is Formulated For

• Adults focused on healthy aging and longevity support
• Individuals seeking to support mitochondrial health and sustainable cellular energy
• Those interested in evidence-informed anti-aging supplements featuring autophagy-supporting compounds
• Adults supporting brain health, immune function, and cardiovascular resilience with polyphenol-rich formulas
• Practitioners looking for a comprehensive mitophagy support formula for active aging patients

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may also want to explore our Anti-Oxidants Supplements collection.

Recommendation: Take three capsules once per day or as directed by your healthcare practitioner.

Serving Size: 3 Capsules
Servings Per Container: 30

Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), magnesium stearate, silicon dioxide.

Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.

Warnings/Cautions: Keep out of reach of children. Keep tightly closed in a cool, dry place.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

†Actiponin® is a registered trademark of TG Biotech Co., Ltd.