Ortho Molecular Products - EstroDIM- 60ct

EstroDIM

Ortho Molecular Products

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OM-630060-1
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EstroDIM by Ortho Molecular Products – Targeted Support for Estrogen Balance and Detoxification

EstroDIM by Ortho Molecular Products is a powerful estrogen balance supplement formulated to promote healthy estrogen metabolism and support natural detox pathways. Combining two of the most researched dietary indoles—DIM (diindolylmethane) and I3C (indole-3-carbinol)—this unique blend helps maintain hormonal balance, supports liver detoxification, and protects cells from oxidative stress. By promoting efficient estrogen detoxification, EstroDIM helps optimize hormonal health and overall well-being for both women and men.

Key EstroDIM Benefits

  • Supports healthy estrogen metabolism and hormonal balance
  • Promotes detoxification of estrogen pathways for optimal liver function
  • Provides cellular antioxidant support to enhance DNA stability
  • Encourages metabolic balance and hormone clearance
  • Aids in maintaining healthy breast, uterine, and prostate tissues

How EstroDIM Works

EstroDIM combines the synergistic actions of Indole-3-Carbinol (I3C) and Diindolylmethane (DIM)—compounds found naturally in cruciferous vegetables like broccoli and kale. Together, these ingredients help:

  • Promote the conversion of estrogen into its beneficial metabolites
  • Support detoxification enzymes that neutralize harmful estrogen compounds
  • Enhance liver function and cellular antioxidant defense
  • Maintain safe estrogen ratios linked to breast and reproductive health

This DIM supplement is made with clinical-grade ingredients for purity and efficacy, ensuring reliable results with minimal side effects.

Who Should Use EstroDIM

EstroDIM is ideal for individuals seeking a safe and effective way to balance estrogen levels, promote hormone detoxification, and support tissue health. It’s especially beneficial for:

  • Women experiencing hormonal fluctuations or PMS
  • Men and women supporting metabolic and liver health
  • Those aiming to maintain bone, joint, and skin health through balanced hormone activity

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may also want to explore our other Hormone support products.

Recommendation: Ortho Molecular suggests taking 1 capsule of EstroDIM per day or as recommended by your healthcare professional.

Serving Size: 1 Capsule
Servings Per Container: 30/60

Amount Per Serving:
Vitamin E (as d-Alpha Tocopherol Succinate USP) 33.5 mg (50 IU)
Dietary Indoles 300 mg
(Total Indole Blend containingIndole-3-Carbinol)
(13C, 200 mg input) and Diindolymethane (DIM 100 mg input) 

Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Calcium Silicate, Stearic Acid, Silicon Dioxide.

Cautions: If you are pregnant or nursing, consult your physician before taking this product.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click here to view Product Info Sheet

References:

  1. Auborn, K. J., Fan, S., et al. (2003). Indole-3-carbinol is a negative regulator of estrogen. Journal of Nutrition, 133(7 Suppl), 2470S-2475S.
  2. Bradlow, H. L., Michnovicz, J. J., et al. (1994). Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiology, Biomarkers & Prevention, 3(7), 591-595.
  3. Chinni, S. R., Li, Y., Upadhyay, S., Koppolu, P. K., & Sarkar, F. H. (2001). Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene, 20(23), 29236.
  4. Chinni, S. R., & Sarkar, F. H. (2002). Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells. Clinical Cancer Research, 8(4), 1228-1236.
  5. Firestone, G. L., & Bjeldanes, L. F. (2003). Indole-3-carbinol and 3,3’-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions. Journal of Nutrition, 133(7 Suppl), 2448S-2455S.
  6. Frydoonfar, H. R., McGrath, D. R., & Spigelman, A. D. (2003). The effect of indole-3-carbinol and sulforaphane on a prostate cancer cell line. ANZ Journal of Surgery, 73(3), 154-156.
  7. Hong, C., Firestone, G. L., & Bjeldanes, L. F. (2002). Bcl-2 family-mediated apoptotic effects of 3,3’-diindolylmethane (DIM) in human breast cancer cells. Biochemical Pharmacology, 63(6), 1085-1097.
  8. Leibelt, D. A., et al. (2003). Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3’-diindolylmethane in Sprague-Dawley rats. Toxicological Sciences, 74(1), 10-21.
  9. Miller, K. (2003). Estrogen and DNA damage: The silent source of breast cancer? Journal of the National Cancer Institute, 95(2), 100-102.
  10. McAlindon, T. E., et al. (2001). Indole-3-carbinol in women with SLE: Effect on estrogen metabolism and disease activity. Lupus, 10(11), 779-783.
  11. Meng, Q., Qi, M., et al. (2000). Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with up-regulation of BRCA1 and E-cadherin/catenin complexes. Journal of Molecular Medicine, 78(3), 155-165.
  12. Meng, Q., et al. (2000). Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. Journal of Nutrition, 130(12), 2927-2931.
  13. Nachshon-Kedmi, M., Yannai, S., Haj, A., & Fares, F. A. (2003). Indole-3-carbinol and 3,3’-diindolylmethane induce apoptosis in human prostate cancer cells. Food and Chemical Toxicology, 41(6), 745-752.
  14. Wong, G. Y., Bradlow, L., et al. (1997). Dose-ranging study of indole-3-carbinol for breast cancer prevention. Journal of Cellular Biochemistry, 28-29, 111-116.
  15. Yuan, F., Chen, D. Z., et al. (1999). Anti-estrogenic activities of indole-3-carbinol in cervical cells: Implication for prevention of cervical cancer. Anticancer Research, 19(3A), 1673-1680.
  16. Zhang, J., et al. (2003). Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer, 103(12), 2465-2471.