K2-D3 5000 120 C by Xymogen

K2-D3 5000 120 C

Xymogen

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XY-K2D35000-120-1
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K2-D3 5000 120 C by Xymogen

K2-D3 5000 120 capsules by Xymogen is recognized for its safety and efficacy in supporting bone joint and muscle health.* It contains two vital vitamins for your bones and heart: K2 and D3.* If you suffer from K2 and D3 deficiencies, this supplement may be able to help.*

Who Should Consider K2-D3 5000 120 Capsules by Xymogen?

K2-D3 5000 120c by Xymogen may support your health if you:

  • want to strengthen your bones*
  • lack vitamin K2- and D3-rich products in your diet*
  • wish to support healthy blood clotting*

K2-D3 5000 120c —Effects

K2-D3 5000 120 capsules may:

  • promote carboxylation of bone proteins, thus supporting bone health*
  • impact arterial calcium deposits, thus supporting cardiovascular health*
  • promote healthy blood clotting*

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Book a FREE product consultation to learn more about K2-D3 5000 120c by Xymogen.

Recommendation:
Xymogen suggests taking one capsule daily, preferably at mealtime, or as directed by your healthcare practitioner.

Serving Size: 1 Capsule
Servings Per Container: 120

Amount Per Serving:
Vitamin D3 (as cholecalciferol) 125 mcg (5,000 IU)
Vitamin K2 (as menaquinone-7) 90 mcg

Other Ingredients: HPMC (capsule), microcrystalline cellulose, ascorbyl palmitate, and silica.

Does Not Contain: Wheat, gluten, yeast, soy protein, dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Caution:
Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Consider total vitamin K intake (food + supplements) if you are taking blood-thinning medication.

Storage:
Keep closed in a cool, dry place out of reach of children.

LEGAL NOTICE: Xymogen's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. covenanthealthproducts.com makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of covenanthealthproducts.com, you may inquire about XYMOGEN by calling (800) 627-6518

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:

  1. Azuma, K., & Inoue, S. (2009). Vitamin K function mediated by activation of steroid and xenobiotic receptor [in Japanese]. Clin Calcium, 19(12), 1770–1778. [PMID: 19949268]
  2. Beulens, J. W., Bots, M. L., Atsma, F., et al. (2009). High dietary menaquinone intake is associated with reduced coronary calcification. Atherosclerosis, 203(2), 489–493. [PMID: 18722618]
  3. Bischoff-Ferrari, H. A., Willett, W. C., Orav, E. J., et al. (2012). A pooled analysis of vitamin D dose requirements for fracture prevention. New England Journal of Medicine, 367(1), 40–49. [PMID: 22762317]
  4. Bolton-Smith, C., McMurdo, M. E., Paterson, C. R., et al. (2007). Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women. Journal of Bone and Mineral Research, 22(4), 509–519. [PMID: 17243866]
  5. Brugè, F., Bacchetti, T., Principi, F., et al. (2011). Olive oil supplemented with menaquinone-7 significantly affects osteocalcin carboxylation. British Journal of Nutrition, 106(7), 1058–1062. [PMID: 21736837]
  6. Geleijnse, J. M., Vermeer, C., Grobbee, D. E., et al. (2004). Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: The Rotterdam Study. Journal of Nutrition, 134(11), 3100–3105. [PMID: 15514282]
  7. Gigante, A., Brugè, F., Cecconi, S., et al. (2012). Vitamin MK-7 enhances vitamin D3-induced osteogenesis in hMSCs: Modulation of key effectors in mineralization and vascularization. Journal of Tissue Engineering and Regenerative Medicine. [PMID: 23109511]
  8. Heaney, R. P., Recker, R. R., Grote, J., et al. (2011). Vitamin D3 is more potent than vitamin D2 in humans. Journal of Clinical Endocrinology & Metabolism, 96(3), E447–E452. [PMID: 21177785]
  9. Igarashi, M., Yogiashi, Y., Mihara, M., et al. (2007). Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. Molecular and Cellular Biology, 27(22), 7947–7954. [PMID: 17875939]
  10. Kanellakis, S., Moschonis, G., Tenta, R., et al. (2012). Changes in parameters of bone metabolism in postmenopausal women following a 12-month intervention period using dairy products enriched with calcium, vitamin D, and phylloquinone (vitamin K1) or menaquinone-7 (vitamin K2): The Postmenopausal Health Study II. Calcified Tissue International, 90(4), 251–262. [PMID: 22392512]
  11. Knapen, M. H., Drummen, N. E., Smit, E., et al. (2013). Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International, 24(9), 2499–2507. [PMID: 23525894]
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  13. Sada, E., Abe, Y., Ohba, R., et al. (2010). Vitamin K2 modulates differentiation and apoptosis of both myeloid and erythroid lineages. European Journal of Haematology, 85(6), 538–548. [PMID: 20887388]
  14. Schurgers, L. J., Teunissen, K. J., Hamulyák, K., et al. (2007). Vitamin K-containing dietary supplements: Comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 109(8), 3279–3283. [PMID: 17158229]
  15. Schurgers, L. J., & Vermeer, C. (2002). Differential lipoprotein transport pathways of K-vitamins in healthy subjects. Biochimica et Biophysica Acta, 1570(1), 27–32. [PMID: 11960685]
  16. Shea, M. K., Booth, S. L., Massaro, J. M., et al. (2008). Vitamin K and vitamin D status: Associations with inflammatory markers in the Framingham Offspring Study. American Journal of Epidemiology, 167(3), 313–320. [PMID: 18006902]
  17. Tsiaras, W. G., & Weinstock, M. A. (2011). Factors influencing vitamin D status. Acta Dermato-Venereologica, 91(2), 115–124. [PMID: 21384086]
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  20. Yamaguchi, M., Taguchi, H., Gao, Y. H., et al. (1999). Effect of vitamin K2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovariectomized rats. Journal of Bone and Mineral Metabolism, 17(1), 23–29. [PMID: 10084398]