Ortho Molecular Products - EstroDIM- 60ct

EstroDIM

Ortho Molecular Products

$28.20
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SKU:
OM-630030
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Minimum Purchase:
1 unit
Maximum Purchase:
4 units
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EstroDIM by Ortho Molecular Products

EstroDIM is a hormone-based supplement designed by Ortho Molecular Products.* It may help you with symptoms of estrogen deficiency, such as fatigue or mood swings.* What is more, it is the only supplement on the market that combines both I3C and DIM—two crucial metabolites found in vegetables.*

Who May Consider EstroDIM by Ortho Molecular Products?

EstroDIM may be for you if you suffer from these symptoms of unbalanced estrogen levels:

  • fatigue*
  • mood swings*
  • hot flashes*
  • irregular or no menstruation*
  • dry skin*

How May EstroDIM Affect You?

EstroDIM by Ortho Molecular Products may have the following impact on your body:

  • supporting estrogen balance*
  • promoting regular estrogen metabolism for women*
  • help detoxify estrogen pathways*
  • provide cellular antioxidant support for DNA stability*

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Book a FREE product consultation to learn more about stroDIM.

Recommendation:
Ortho Molecular suggests taking 1 capsule of EstroDIM per day or as recommended by your health care professional.

Serving Size: 1 Capsule
Servings Per Container: 30/60

Amount Per Serving:
Vitamin E (as d-Alpha Tocopherol Succinate USP) 33.5 mg (50 IU)
Dietary Indoles 300 mg
(Total Indole Blend containingIndole-3-Carbinol)
(13C, 200 mg input) and Diindolymethane (DIM 100 mg input) 

Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, CalciumSilicate, Stearic Acid, and Silicon Dioxide.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click here to view Product Info Sheet

References:

  1. Auborn, K. J., Fan, S., et al. (2003). Indole-3-carbinol is a negative regulator of estrogen. Journal of Nutrition, 133(7 Suppl), 2470S-2475S.
  2. Bradlow, H. L., Michnovicz, J. J., et al. (1994). Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiology, Biomarkers & Prevention, 3(7), 591-595.
  3. Chinni, S. R., Li, Y., Upadhyay, S., Koppolu, P. K., & Sarkar, F. H. (2001). Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene, 20(23), 29236.
  4. Chinni, S. R., & Sarkar, F. H. (2002). Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells. Clinical Cancer Research, 8(4), 1228-1236.
  5. Firestone, G. L., & Bjeldanes, L. F. (2003). Indole-3-carbinol and 3,3’-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions. Journal of Nutrition, 133(7 Suppl), 2448S-2455S.
  6. Frydoonfar, H. R., McGrath, D. R., & Spigelman, A. D. (2003). The effect of indole-3-carbinol and sulforaphane on a prostate cancer cell line. ANZ Journal of Surgery, 73(3), 154-156.
  7. Hong, C., Firestone, G. L., & Bjeldanes, L. F. (2002). Bcl-2 family-mediated apoptotic effects of 3,3’-diindolylmethane (DIM) in human breast cancer cells. Biochemical Pharmacology, 63(6), 1085-1097.
  8. Leibelt, D. A., et al. (2003). Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3’-diindolylmethane in Sprague-Dawley rats. Toxicological Sciences, 74(1), 10-21.
  9. Miller, K. (2003). Estrogen and DNA damage: The silent source of breast cancer? Journal of the National Cancer Institute, 95(2), 100-102.
  10. McAlindon, T. E., et al. (2001). Indole-3-carbinol in women with SLE: Effect on estrogen metabolism and disease activity. Lupus, 10(11), 779-783.
  11. Meng, Q., Qi, M., et al. (2000). Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with up-regulation of BRCA1 and E-cadherin/catenin complexes. Journal of Molecular Medicine, 78(3), 155-165.
  12. Meng, Q., et al. (2000). Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. Journal of Nutrition, 130(12), 2927-2931.
  13. Nachshon-Kedmi, M., Yannai, S., Haj, A., & Fares, F. A. (2003). Indole-3-carbinol and 3,3’-diindolylmethane induce apoptosis in human prostate cancer cells. Food and Chemical Toxicology, 41(6), 745-752.
  14. Wong, G. Y., Bradlow, L., et al. (1997). Dose-ranging study of indole-3-carbinol for breast cancer prevention. Journal of Cellular Biochemistry, 28-29, 111-116.
  15. Yuan, F., Chen, D. Z., et al. (1999). Anti-estrogenic activities of indole-3-carbinol in cervical cells: Implication for prevention of cervical cancer. Anticancer Research, 19(3A), 1673-1680.
  16. Zhang, J., et al. (2003). Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells. Cancer, 103(12), 2465-2471.